Manuscript Writing for Clinical Researchers: My 4-Step Framework (PART III)

Table of Contents

We have now traversed the dense forests of “dump” and scaled the organized mountains of “lump” (See parts I & II of manuscript writing). This is the final part (part III) of our three-part manuscript writing series. Now, let’s discuss the final two steps of our manuscript writing journey, where we will JUMP across the rivers of refinement and give our manuscript that final BUMP to let it truly shine. Buckle up, because these next steps are what will elevate your manuscript from good to outstanding.

You can follow along with our manuscript writing template here!đź“ť

STEP 3- JUMP: Creating the Flow

You’ve offloaded your thoughts (that was the ‘dump’) and arranged them systematically (thanks to the ‘lump’). Now, let’s give it rhythm and resonance. Welcome to the ‘JUMP’ phase. Here, we refine our manuscript to ensure every paragraph flows like a symphony, hitting all the right notes to convey your scientific findings with grace.

One Idea, One Paragraph

Think of each paragraph as a mini-story. Each should convey one clear idea or argument. The topic sentence acts as your headline, setting the stage for what’s to follow (as we described in the “LUMP”). We can certainly move from broad to specific within a paragraph. However, if your paragraph seems to be juggling multiple ideas, it’s time to split it.

Watch Out for Those Repetitive Beats

Repetition can be either redundant or reinforcing. The former is superfluous, potentially boring your reader, while the latter emphasizes a key point. As you review your manuscript, identify places where you might be reiterating the same idea without adding value. Can two similar points be condensed? Remember, the key is to get an idea across efficiently.

Seamless Transitions: Your Manuscript’s Magic Carpet

Smooth transitions are like that delightful bridge in your favorite song. They connect your thoughts effortlessly, ensuring your reader glides from one idea to the next with ease. Whether you’re linking paragraphs or just individual sentences, clear transitions guide your reader through your narrative smoothly. You should hold your reader’s hand and walk them through as you introduce a new idea so that they don’t stumble.

Balancing Your Sentences: The Long and Short of It

While the occasional long, poetic sentence can add depth to literary writing, that is not the case with academic writing. Here, the sentences generally need to be shorter (barring the introductory sentence for the paragraph which can sometimes be long while trying to emphasize the gist of the paragraph. Again one sentence, one idea is a good rule of thumb to keep in mind. If this is not the case, time to break it down.

Speak The Language of Your Audience

Your tone and style need to resonate with your target audience- always make it EASY for them. This doesn’t mean dumbing things down, but rather ensuring clarity and avoiding excessive jargon unless it’s absolutely essential. Always keep your target audience at the forefront of your mind.


In the ‘JUMP’ phase, the devil is in the details. You’re not just sharing facts and findings; you’re telling a story – your research story. And just like any good tale, it needs rhythm, clarity, and impeccable flow to engage and educate your audience. After this meticulous refining, we’re almost ready to showcase our masterpiece to the world. Stay tuned for the final touches!

Step 4- BUMP: Getting it Ship-Ready

Okay, so you’ve poured out your ideas, structured them neatly, and refined them for a smooth flow. You’re almost there! However, before your manuscript is ready to shine in the limelight, it needs a final ‘BUMP’ – a thorough polish to ensure everything is in impeccable shape. This is where we dive deep into the nitty-gritty of grammar, consistency, and all those tiny details that contribute to a well-crafted manuscript.

Grammar & Spelling: The Nuts and Bolts

In the vast sea of research, it’s the small grammatical errors or misspellings that can quickly sink your manuscript’s credibility (it can give a sense of low attention to detail and translate to lower confidence in your findings). It might sound basic, but you’d be surprised how often these can slip through. Tools like Grammarly, Prowriting Aid, or Microsoft Word’s in-built spell-check can be lifesavers here.

Consistency is Key

Whether it’s the font size, the way you’ve structured your headings, or even the abbreviations you’re using, consistency matters. It not only makes your manuscript look professional but also ensures a seamless reading experience for your audience. It’s a silent shoutout to your meticulousness as a researcher!

NOTE: Remember the “Halo” effect. One bad aspect of the manuscript can affect the overall impression of your research. Avoid this!

Checking Citations: Giving Credit Where It’s Due

Your research doesn’t exist in a vacuum. It’s built upon the hard work of countless others, and it’s crucial to acknowledge that. Also, remember that some of these researchers are also going to be reviewing your research, so cite broadly and make sure you don’t at least leave out a landmark paper for the topic. Ensure that every claim or reference you make is backed up with a relevant citation. Tools like Zotero, EndNote, or Mendeley can streamline this process and make your job a lot easier. In today’s day and age, no one should be putting in citations manually (even if there are just five)- chances are that you will have to resubmit your manuscript to another journal and they will require a different citation style. The citation managers make this process a breeze.

A Picture Speaks a Thousand Words: Tables & Figures

These visual aids can often speak louder than words. They offer a snapshot of your findings and can greatly enhance understanding. Make them clear, consistent, and compelling. They should be clearly labeled, consistently formatted, and data points should be easy to read.


At the ‘BUMP’ phase, we’re ironing out the creases, ensuring every element of your manuscript is aligned to perfection. It’s this final layer of polish that transforms a good piece of work into a great one. So, get your magnifying glass out and scrutinize every detail. Once you’re done, take a step back and admire the polished gem that is your research manuscript. Ready to make an impact? Publish away, my friend!

Concluding Our Manuscript Writing Journey

We’ve taken a journey together, navigating the intricate pathways of manuscript writing. But, as with any skill, the real secret lies in actually doing it. Theory and strategies are your roadmap, but only by stepping on the gas and driving forward will you truly progress.

Each iteration, every draft you write, and every revision you make are stepping stones to mastery. Yes, it might seem daunting initially. There might be moments of self-doubt or the temptation to settle for ‘good enough’. But remember, excellence is a habit, and habits are forged through repetition.

The journey of manuscript writing is just as important as the destination. The feedback, the corrections, and even the rejections – they’re all part of the learning curve. Embrace them. Refine your approach with each attempt, and watch as the daunting mountain of manuscript writing transforms into a rewarding climb.

In the end, it’s all about rolling up your sleeves and getting your hands dirty in the rich soil of research and writing. Because with each attempt, you’re not just crafting a paper; you’re honing a craft, building a legacy, and advancing the world of clinical research, one manuscript at a time.

Ready to make your mark? Start writing, keep refining, and let your research shine!✨🖋️

PS: Don’t forget to grab your manuscript writing template here!đź“ť

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