MY ACADEMIC BIO

Name:             Paras Karmacharya, MD MS

Office Address:                                 Division of Rheumatology and Immunology 
                                                                Vanderbilt University Medical Center
                                                                1161 21st Avenue South
                                                                Nashville, TN 37232

ORCID ID:                                            https://orcid.org/0000-0003-1034-1530

LinkedIn:                                            https://www.linkedin.com/in/paras-karmacharya099

 

Education

College:
  • Xavier’s Campus (Kathmandu, Nepal), Intermediate of Science (Biology), 05/2000- 06/2002
 
Professional or graduate:
  • Kathmandu University School of Medical Sciences (Kavre, Nepal), Bachelor of Medicine and Bachelor of Surgery, 02/2004-08/2009

Postgraduate Training:
  • Residency, Internal Medicine, Reading Health System (West Reading, PA), 06/2012-06/2015
  • Fellowship, Rheumatology, Mayo Clinic (Rochester, MN), 07/2017- 06/2020
  • Master’s Degree in Clinical and Translational Science (CCaTS), Mayo Clinic (Rochester, MN), 07/2018-02/2021
  • Post-doctoral Fellow, Musculoskeletal Research and Training Program, Mayo Clinic (Rochester, MN), 07/2020-06/2021

Personal Statement:

I am a Physician-Scientist and Assistant Professor of Medicine in the Division of Rheumatology at the Vanderbilt University. I lead the psoriatic arthritis (PsA) and spondyloarthritis (SpA) clinical and research program at VUMC. I am part of the Psoriatic Arthritis Research Consortium (PARC) and NEtwork for Research and Development in Spondyloarthritis (NERDS), which include five PsA and SpA-dedicated clinics in the US aimed to improve patient-centered care and advance personalized medicine in PsA and SpA. The mission of my clinical and research program is to improve outcomes in PsA and SpA by developing better treatment strategies, and to understand the factors leading to the development of PsA and SpA enabling early intervention. I aim to combine traditional epidemiology, bioinformatics, human genetics, and machine learning/AI to achieve my long-term goal of leading patient-centered, pragmatic research in real-world PsA and SpA patients and advancing personalized medicine.

Much of my recent work has focused on understanding phenotypes, comorbidities, and long-term outcomes in PsA and axial SpA using advanced statistical and machine learning algorithms. I’ve received the NIH K23, Rheumatology Research Foundation (RRF), Spondyloarthritis Research and Treatment Network (SPARTAN), Spondylitis Association of America (SAA), Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), and Assessment of spondyloarthritis international society (ASAS) grants to understand different phenotypes and comorbidities in spondyloarthritis and associated outcomes.

 

Licensure and Certification

Licensure:

  • Nepal Medical Council (Nepal), Permanent Registration No. 8686, 2010-Current
  • Pennsylvania, Medical License No. MD 455489, 06/2015-06/2017
  • Minnesota Medical License, License No. 61860, 02/2017-06/2021
  • Tennessee State Medical License, License No. 63338, 06/2024-Current

Certification:
  • ABIM, Internal Medicine, 10/08/2015
  • ABIM, Rheumatology, 12/05/2019

 

Academic Appointments

  • Instructor in Medicine, Division of Rheumatology, Vanderbilt University Medical Center (Nashville, TN), 07/2021-6/2023
  • Assistant Professor of Medicine, Division of Rheumatology, Vanderbilt University Medical Center (Nashville, TN), 07/2023-

 

Hospital Appointments

  • Vanderbilt University Hospital (Nashville, TN), 07/01/2021-Current

 

Professional Organizations

  • Member, Rheumatology Research Foundation, 2014-Current
  • Member, American College of Rheumatology, 2015-Current
  • Member, Spondyloarthritis Research & Treatment Network, 2019-2022 (Trainee Member), 2023-Current (Associated Member)
  • Associate Member, Assessment of Spondyloarthritis International Society, 2021-Current
  • Member, Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Young-GRAPPA, 2021-current
  • Physician-Scientist Member, National Psoriasis Foundation, 2022-Current

 

Professional Activities

Intramural: 
  • N/A
 
Extramural:
  • Peer-Reviewer, Annals of Medicine, 07/2014-Current
  • Peer-Reviewer, BMJ Case Reports, 02/2014-Current
  • Peer-Reviewer, Seminars in Arthritis and Rheumatism, 08/2017-Current
  • Peer-Reviewer, Journal of Clinical Rheumatology, 07/2018-Current
  • Peer-Reviewer, Case Reports in Rheumatology, 09/2019-Current
  • Peer-Reviewer, Arthritis Care & Research, 09/2019-Current
  • Peer-Reviewer, ACR Open Rheumatology, 03/2020-Current
  • Peer-Reviewer, Journal of Rheumatology, 06/2020-Current
  • Peer-Reviewer, Arthritis Research & Therapy, 08/2020-Current
  • Peer-Reviewer, The Lancet Rheumatology, 09/2020-Current
  • Peer-Reviewer, Journal of Psoriasis and Psoriatic Arthritis, 09/2020-Current
  • Peer Reviewer, Mayo Clinic Proceedings (Rochester, MN), 12/2021-Current
  • Abstract Reviewer, Spondyloarthritis Section, American College of Rheumatology Annual Conference (virtual), 2021
  • Abstract review co-Chair, Spondyloarthritis Section, American College of Rheumatology Annual Conference, 2022-2024
  • Member, Rheumatology Research Foundation Early Career Investigator Subcommittee, 2023-Current
  • Reviewer and Expert commentator, Medscape Axial Spondyloarthritis Q&A, 2023-2024
  • Core committee member, Axial Spondyloarthritis American College of Rheumatology guidelines, 2023-current
  • Grant reviewer, National Psoriasis Foundation, 2025-current
 
Continuing Medical Education:
  • Invited extra-mural talks:
    • Lecturer, “Lack of Prevalence Data in BIPOC Access to Care”, Skin of Color Dermatology- Rheumatology Collaborative National Psoriasis Foundation (virtual), 11/10/2021
    • Podcast guest, “PCP Series: Overview and Diagnosis of PsA: Part 1 & 2”, Psound Bytes CME, National Psoriasis Foundation, 3/17 and 4/20/2022
    • Lecturer “Psoriatic Arthritis 101” organized by the National Psoriasis Foundation for the Division of Connective Tissue Disease (Rheumatology), University of Tennessee Health Science Center, Memphis, TN, 2/07/2023
    • Lecturer “Challenges in Psoriatic Disease” at Dermatology Grand Rounds, Vanderbilt University Medical Center (Nashville, TN), 3/02/2023
    • Lecturer “Defining clinical subphenotypes in axial spondyloarthritis & psoriatic arthritis” Arthritis Web Seminar Series organized by Schroeder Arthritis Institute, 3/26/2024
    • Oral presentation at ACR annual meeting 2023 “Identifying Distinct Phenotypes in Psoriatic Arthritis: A Study from the Psoriatic Arthritis Research Consortium (PARC) Cohort” 11/13/2023.
    • Oral presentation at the GRAPPA annual meeting 2024 “Multimorbidity in Psoriasis as a Risk Factor for Psoriatic Arthritis: A Population-Based Study” 7/13/2024.
    • Oral presentation at PPACMAN (Psoriasis & Psoriatic Arthritis Clinics Multicenter Advancement Network) meeting 2024 “Psoriatic arthritis phenotype clusters and their association with treatment response: A Study from the Psoriatic Arthritis Research Consortium (PARC) Cohort” 12/14/2024.
    • Oral Presentation at Tennessee Rheumatology Society meeting 2025 “Psoriatic arthritis phenotype clusters and their association with treatment response: A Study from the Psoriatic Arthritis Research Consortium (PARC) Cohort” 2/28/2025
  • Intra-mural talks for Division of Rheumatology:
    • Lecturer, “Individualized Management Strategies in Psoriatic Arthritis,” Rheumatology Grand Rounds, Division of Rheumatology and Immunology, Vanderbilt University Medical Center (Nashville, TN), 10/14/2021
    • “Treat to Target in Spondyloarthritis”, Journal Club, Rheumatology Grand Rounds, Division of Rheumatology and Immunology, Vanderbilt University Medical Center (Nashville, TN), 10/28/2021
    • Lecturer, “Psoriasis and psoriatic arthritis risk-stratification in electronic health records”, Dermatology Research Round, Division of Dermatology, Vanderbilt University Medical Center (Nashville, TN), 4/08/2022
    • Lecturer “Psoriatic Arthritis 101” organized by the National Psoriasis Foundation for the Division of Connective Tissue Disease (Rheumatology), University of Tennessee Health Science Center, Memphis, TN, 2/07/2023
    • Lecturer “Therapeutic Drug Monitoring in Chronic Immune Mediated Inflammatory Diseases”, Journal Club, Rheumatology Grand Rounds, Division of Rheumatology and Immunology, Vanderbilt University Medical Center (Nashville, TN), 2/23/23
 
Special Awards or Recognition:
  • Rheumatology Research Foundation Medical and Pediatric Resident Research Award, 2014
  • Philip S. Hench Award for Outstanding Achievement as a Subspecialty Fellow in Rheumatology, 2020
  • EULAR E-Congress E-Bursary Winner, 2020
  • Represented National Psoriasis Foundation at the Capitol Hill (virtual), 2021
  • Invited Speaker, “2021 Derm-Rheum Collaborative with a Focus on Skin of Color,” National Psoriasis Foundation (virtual), 11/2021
  • 2024 SAA/Jane Bruckel Early Career Investigator in AxSpA Award, 2024

 

Teaching Activities

Medical School Courses:
  • N/A
 
Graduate School Courses:
  • N/A

 

Clinical Teaching for fellows and residents: nature and frequency

  • Lecturer, Critically Reviewed Manuscripts on “Treat to Target in Spondyloarthritis,” Rheumatology Journal Club, Division of Rheumatology and Immunology, Vanderbilt University Medical Center (Nashville, TN), 10/2021
  • Lecturer, “Axial Spondyloarthritis: Diagnosis & Assessment,” Rheumatology Fellows Didactics, Division of Rheumatology and Immunology, Vanderbilt University Medical Center (Nashville, TN), 12/2021
  • Faculty, Internal medicine lecture “Curbsider Approach to Psoriatic Arthritis”, 4/12/2022
  • Lecturer, “Spondyloarthritis Primer for Rheumatology Fellows”, Rheumatology fellow’s lectures, Division of Rheumatology and Immunology, Vanderbilt University Medical Center (Nashville, TN), 7/07/2022, 7/29/2023
  • Faculty, Fellows’ Landmark Trial Series for Spondyloarthritis, 10/05/2022, 9/20/2023, 10/04/2023
  • Lecturer “Axial spondyloarthritis guidelines and beyond”, Rheumatology fellow’s lectures, Division of Rheumatology and Immunology, Vanderbilt University Medical Center (Nashville, TN), 2/21/2024
  • Supervise and Teach Medical Residents and Medical Students:
  • rheumatology outpatient rotation- 11/19/2021- current (Friday afternoons, ~2 times/month)
  • rheumatology inpatient rounds (during inpatient rotation once/year)- 9/01/21- 9/15/21
 

Research Supervision

  • Ravi Shahukhal, MD, Rheumatology Fellow, University of Central Florida (Orlando, FL), Summer 2020 (Position during supervision: Academic Hospitalist, Lakes Region General Hospital (Laconia, NH))
 
Type of Research/Mentoring:  Systematic Review and Meta-Analysis
Scientific Publications from Mentored Period:  4 publications, 2 poster presentations
  • Rashmi Poudel, MD, Rheumatology Fellow, University of California (San Diego, CA), 6/2016-Current (Position during supervision: Internal Medicine Resident, Tower Health (Reading, PA)

Type of Research/Mentoring: Epidemiology and Health Outcomes
Scientific Publications from Mentored Period:  6 publications, 20 poster presentations
  • Haseeb Chaudhary, MD, Rheumatology Fellow, Case Western Reserve University (Cleveland, OH), 8/2020-8/2021(Position during supervision: Internal Medicine Resident, Tower Health (Reading, PA))

Type of Research/Mentoring: Systematic Review and Meta-Analysis
Scientific Publications from Mentored Period: 1 publication, 1 poster
  • Rikesh Chakradhar, MD, Resident/Fellow, Pediatric Neurology Program, St. Christopher’s Pediatric Hospital (Philadelphia, PA), 10/2020-5/2021 (Position during supervision: Research Trainee, Division of Rheumatology, Mayo Clinic (Rochester, MN)
Type of Research/Mentoring:  Epidemiology of Psoriasis and Psoriatic Arthritis
Scientific Publications from Mentored Period:  2 publications, 2 poster presentations
  • Sonia Gupta, MD, Rheumatology Fellow, University of Utah (Salt Lake City, UT), 7/2021-Current (Position during supervision: Internal Medicine Resident, Creighton University (Omaha, NE)) Type of Research/Mentoring: Systemic Review and Meta-Analysis Scientific Publications from Mentored Period: 1 publication, 1 poster
  • Avery Fortier, MD, Research trainee, Division of Rheumatology, Vanderbilt University Medical Center, 12/2021-4/2024 (Position during supervision: Undergraduate student, Vanderbilt University) Type of Research/Mentoring: Developing electronic health record algorithms to identify patients with psoriatic arthritis and psoriasis, medical record review, interpretation of data, and abstract presentation. Scientific Publications from Mentored Period: 1 poster publication (won undergraduate scholarship from the American College of Rheumatology Convergence meeting 2024)
  • Gyaljin Sherpa, MD, Post-doctoral research fellow, Division of Rheumatology, Vanderbilt University Medical Center, 12/2023-Current (Position during supervision: Internal Medicine Applicant, Kathmandu University Medical Center (Kathmandu, Nepal)) Type of Research/Mentoring: Original research from synthetic derivative on psoriatic arthritis and treatment response, data collection, interpretation, and abstract writing. Scientific Publications from Mentored Period: abstract submitted for poster presentation, Rheumatology Research Workshop 2024


Research Program

Ongoing Research Support:

Scientist Development Award (PI)                           $125,000                     07/2022-06/2025

Rheumatology Research Foundation (RRF)

Defining psoriatic arthritis phenotypes and probability of response to therapy

This project grant aims to identify PsA phenotypes and PsA patients with a high probability of responding to therapy and those with a low probability of responding to therapy from our multicenter longitudinal cohort, the Psoriatic Arthritis Research Consortium (PARC, R01 AR072363, PI Ogdie).

Effort:  55%

Role: PI

1K23AR082990-01 (PI)                                             $163,258/ year                        07/2023-06/2028

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Association of Phenotypes and Genotype with Treatment Response in Psoriatic Arthritis

To use two unique real-world PsA cohorts to better understand clinical and genetic heterogeneity in PsA and to identify those who are more likely or less likely to respond to therapy.

Effort: 75%

Role: PI

Discovery Grant (PI)                                                  $75,000                       07/2023-06/2025

National Psoriasis Foundation

Personalized Medicine in Psoriatic Arthritis:  The Role of Obesity

To use an electronic health record based PsA cohort linked to a genetic biorepository to examine the association of polygenic risk score for obesity with comorbidities and treatment response in PsA beyond BMI.

Effort: 10%

Role: PI


Completed Research Support:

Fellowship Grant (PI)                                                 $27,000                       01/2021- 06/2023

Assessment of spondyloarthritis international society (ASAS)

Accumulation of Comorbidities and Association with Disease Activity and Functional Impairment in Ankylosing Spondylitis: data from the PSOAS cohort

This mentored fellowship grant aims to define existing and emerging morbidities in patients with AS and their effects on disease outcomes in AS using the PSOAS cohort.

Effort:  0%

Role: PI, Mentor: Lianne S. Gensler, MD, University of California, San Francisco, CA

Fellowship Pilot Grant (PI)                                        $10,000                       08/2019- 07/2021 

Spondyloarthritis Research and Treatment Network (SPARTAN)

Risk of Multimorbidity in Spondyloarthritis: A UK population-based cohort study

This mentored pilot project grant aims to define the incidence, prevalence, and trends of multimorbidity in patients with AS compared to patients with PsA as well as age- and sex-matched comparators without AS or PsA in the general population using The Health Improvement Network (THIN) database.

Effort: 0%

Role: PI, Mentor: Alexis Ogdie, MD MSCE, University of Pennsylvania, Philadelphia, PA

T32 AR56950 Grant, Mayo Clinic (NIAMS)                                                07/2020- 06/2021

Musculoskeletal Research Training Program

The aim of this grant is to better define the comorbidities, their interactions, and effect on disease outcomes in spondyloarthritis using the multicenter Prospective Study of Outcomes in Ankylosing Spondylitis (PSOAS) cohort.

Effort: 100%

Role: Fellow

Pilot Research Grant 2020 (PI)                                  $25,000                       07/2020-06/2022

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)

Multimorbidity in psoriasis as a risk factor for psoriatic arthritis

This pilot project grant aims to define existing and emerging morbidities in patients with psoriasis as a risk factor for development of PsA using data from the Rochester Epidemiology Project (REP).

Effort: 0%

Role: PI

Fellowship Pilot Grant (PI)                                        $10,000                       08/2021- 12/2022 Spondyloarthritis Research and Treatment Network (SPARTAN)

Effect of Biologics in Subgroups of Axial Spondyloarthritis Based on MRI and CRP: A Subgroup Analysis by Objective Signs of Inflammation

This pilot project grant aims to examine treatment response in axSpA patients (both radiographic and non-radiographic) with differing inflammatory burdens based on MRI/CRP. Using data from available axSpA RCTs (phase II and III) with baseline MRI/CRP data, we plan to perform a systematic review and meta-analysis of improvement in disease activity in drug vs. placebo group in the 4 different subgroups (MRI+/CRP+, MRI+/CRP-, MRI-/CRP+, MRI-/CRP-).

Effort: 0%

Role: PI

T32AR059039

Vanderbilt University Medical Center (NIAMS)                                          07/2021-06/2022

Interdisciplinary Training in Rheumatic Diseases

The aim of this grant is to develop and validate electronic health record (EHR) algorithms that accurately identify patients with psoriasis (psO) and psoriatic arthritis (PsA) using Vanderbilt’s synthetic derivative and examine differences in comorbidities in PsA with psO and the general population using phenome-wide association study.

Effort: 80%

Role: Fellow

 

Publications and Presentations

Articles in Refereed Journals:  (Senior/First/Total: 11/22/83)

  1. Karmacharya P, Mainali NR, Aryal MR, Lloyd B. Recurrent case of ibuprofen-induced aseptic meningitis in mixed connective tissue disease. BMJ Case Rep. 2013 Apr 30;2013. pii: bcr2013009571. PMID: 23632618.
  2. Karmacharya P, Aryal MR. Heart stopping tick. World J Cardiol. 2013 May 26;5(5):148-50. PMID: 23710302.
  3. Aryal MR, Karmacharya P, Bhandari N, Subedee A. You are too brash if you ignore the rash. BMJ Case Rep. 2013 Sep 3;2013. pii: bcr2013200506. PMID: 24001734.
  4. Karmacharya P, Aryal MR, Donato A. Mesenteric vein thrombosis in a patient heterozygous for factor V Leiden and G20210A prothrombin genotypes. World J Gastroenterol. 2013 Nov 21;19(43):7813-5. PMID: 24282370.
  5. Pathak R, Karmacharya P, Aryal MR, Smith-Coleman KE. Necrobiosis lipoidica. J Community Hosp Intern Med Perspect. 2013 Dec 17;3(3-4). PMID: 24392215.
  6. Karmacharya P, Shah K, Pathak R, Ghimire S, Alweis R. Touch me not. J Community Hosp Intern Med Perspect. 2014 Feb 17;4. PMID: 24596647.
  7. Aryal MR, Pathak R, Karmacharya P, Donato AA. Seasonal and regional variation in Takotsubo cardiomyopathy. Am J Cardiol. 2014 May 1;113(9):1592. PMID: 24731655.
  8. Roy S, Karmacharya P, Aryal MR. Diagnosis of intestinal ascariasis in modern era. BMJ Case Rep. 2014 Apr 16;2014. pii: bcr2013200529. PMID: 24739652.
  9. Pathak R, Karmacharya P, Aryal MR, Donato A. Costs and mortality associated with atrial fibrillation complicated by myocardial infarction in the United States. Int J Cardiol. 2014 Jun 1;174(1):186. PMID: 24746499.
  10. Pathak R, Karmacharya P, Salman A, Alweis R. An unusual cause of hypoglycemia in a middle-aged female after bariatric surgery. J Community Hosp Intern Med Perspect. 2014 Apr 14;4. PMID: 24765253.
  11. Pathak R, Karmacharya P, Aryal MR, Donato AA. Weekend versus weekday mortality in myocardial infarction in the United States: data from healthcare cost and utilization project nationwide inpatient sample. Int J Cardiol. 2014 Jul 1;174(3):877-8 PMID:24836683.
  12. Ukaigwe A, Karmacharya P, Donato A. A Gut Gone to Pot: A Case of Cannabinoid Hyperemesis Syndrome due to K2, a Synthetic Cannabinoid. Case Rep Emerg Med. 2014;2014:167098. PMID:24872901.
  13. Aryal MR, Hakim FA, Ghimire S, Ghimire S, Giri S, Pandit A, Bhandari Y, Bhandari N, Pathak R, Karmacharya P, Pradhan R. Left atrial appendage aneurysm: a systematic review of 82 cases. Echocardiography. 2014 Nov;31(10):1312-8. PMID: 24976376.
  14. Aryal MR, Ukaigwe A, Pandit A, Karmacharya P, Pradhan R, Mainali NR, Pathak R, Jalota L, Bhandari Y, Donato A. Meta-analysis of efficacy and safety of rivaroxaban compared with warfarin or dabigatran in patients undergoing catheter ablation for atrial fibrillation. Am J Cardiol. 2014 Aug 15;114(4):577-82. PMID: 24998087.
  15. Pathak R, Aryal MR, Karmacharya P, Donato AA. Mortality in intra-aortic balloon pump therapy in patients with ST elevation myocardial infarction and cardiogenic shock: data from nationwide inpatient sample. Int J Cardiol. 2014 Sep;176(1):279-80. PMID: 25037696.
  16. Pathak R, Karmacharya P, Aryal MR, Alweis R. Iatrogenesis imperfecta: stroke caused by accidental carotid artery catheterization. J Vasc Access. 2014 Nov-Dec;15(6):537-40. PMID:25041919.
  17. Pathak R, Bhatt VR, Karmacharya P, Aryal MR, Alweis R. Trends in blood-product transfusion among inpatients in the United States from 2002 to 2011: data from the Nationwide Inpatient Sample. J Hosp Med. 2014 Dec;9(12):800-1. PMID: 25100306.
  18. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Seasonal variation in the presentation of thyroid cancer in the USA: an analysis of the Surveillance, Epidemiology and End Results Registry. Cancer Causes Control. 2014 Nov;25(11):1583-5. PMID:25135614.
  19. Karmacharya P, Pathak R, Shrestha P, Alweis R. The red hearing: swollen ear in a patient with ulcerative colitis. J Community Hosp Intern Med Perspect. 2014 Jul 31;4. PMID: 25147631
  20. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Seasonal and regional variation of thrombotic thrombocytopenic purpura in the United States: insights from the Nationwide Inpatient Sample. Am J Hematol. 2015 Jan;90(1):E24. PMID: 25229615.
  21. Ukaigwe A, Karmacharya P, Mahmood M, Pathak R, Aryal MR, Jalota L, Donato AA. Meta-analysis on efficacy of statins for prevention of contrast-induced acute kidney injury in patients undergoing coronary angiography. Am J Cardiol. 2014 Nov 1;114(9):1295-302. PMID: 25239829.
  22. Aryal MR, Karmacharya P, Pandit A, Hakim F, Pathak R, Mainali NR, Ukaigwe A, Mahmood M, Badal M, Fortuin FD. Dual versus single antiplatelet therapy in patients undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis. Heart Lung Circ. 2015 Feb;24(2):185-92. PMID: 25240570.
  23. Karmacharya P, Donato AA, Aryal MR, Pathak R, Goonewardene M, Valent P. All systems red. Am J Hematol. 2015 Apr;90(4):356-60. doi: 10.1002/ajh.23869. Epub 2014 Oct 25. PMID: 25294166.
  24. Pathak R, Supplee S, Aryal MR, Karmacharya P. Warfarin induced sublingual hematoma: a Ludwig angina mimic. Am J Otolaryngol. 2015 Jan-Feb;36(1):84-6. PMID: 25301667.
  25. Pandit A, Karmacharya P, Pathak R, Giri S, Aryal MR. Efficacy of NSAIDs for the prevention of acute mountain sickness: a systematic review and meta-analysis. J Community Hosp Intern Med Perspect. 2014 Sep 29;4(4). PMID: 25317267.
  26. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Incidence trend of esophageal squamous cell carcinoma: an analysis of Surveillance Epidemiology, and End Results (SEER) database. Cancer Causes Control. 2015. Jan;26(1):159-61. PMID:25376829.
  27. Karmacharya P, Bhandari N, Aryal MR, Pandit AA, Pathak R, Ghimire S, Shrestha P, Bhatt VR. Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin’s Lymphoma. J Community Hosp Intern Med Perspect. 2014 Nov 25;4(5):25821. PMID: 25432655
  28. Pathak R, Giri S, Karmacharya P, Aryal MR, Donato AA. Comparison between saddle versus non-saddle pulmonary embolism: insights from nationwide inpatient sample. Int J Cardiol. 2015 Feb 1;180:58-9. PMID: 25438212.
  29. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Lack of “weekend effect” on mortality for pulmonary embolism admissions in 2011: data from nationwide inpatient sample. Int J Cardiol. 2015 Feb 1;180:151-3. PMID: 25438238.
  30. Pathak R, Pandit A, Karmacharya P, Aryal MR, Ghimire S, Poudel DR, Shamoun FE. Meta-analysis on risk of bleeding with apixaban in patients with renal impairment. Am J Cardiol. 2015 Feb 1;115(3):323-7. PMID: 25527282.
  31. Pathak R, Giri S, Karmacharya P, Aryal MR. Obstructive sleep apnea syndrome and secondary polycythemia: analysis of the nationwide inpatient sample. Sleep Med. 2015 Jan;16(1):205-6. PMID: 25534581.
  32. Pathak R, Giri S, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Mortality, length of stay, and health care costs of febrile neutropenia-related hospitalizations among patients with breast cancer in the United States. Support Care Cancer. 2015 Mar;23(3):615-7. PMID: 25556610.
  33. Shrestha R, Khanal R, Aryal MR, Pathak R, Karmacharya P, Naqi M, Murukutla S, Bhatt VR, Gottesman A. Fibroid degeneration in a postmenopausal woman presenting as an acute abdomen. J Community Hosp Intern Med Perspect. 2015 Feb 3;5(1): 25917.PMID: 25656665.
  34. Poudel DR, Karmacharya P, Pathak R, Ghimire S, Khanal R, Alweis R. Colloid cyst: an unusual cause of seizure. J Community Hosp Intern Med Perspect. 2015 Feb 3;5(1):26311. PMID:25656672.
  35. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Second primary malignancies in Waldenstrom’s macroglobulinemia: a US population-based study. Cancer Causes Control. 2015 Apr;26(4):645-7. PMID: 25732345.
  36. Giri S, Pathak R, Yarlagadda V, Karmacharya P, Aryal MR, Martin MG. Meta-analysis of 21- versus 22-G aspiration needle during endobronchial ultrasound-guided transbronchial needle aspiration. J Bronchology Interv Pulmonol. 2015 Apr;22(2):107-13. PMID: 25887005.
  37. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Impact of hospital volume on outcomes of patients undergoing chemotherapy for acute myeloid leukemia: a matched cohort study. Blood. 2015 May 21;125(21):3359-60. PMID: 25999448.
  38. Poudel DR, Pathak R, Karmacharya P, Ghimire S, Khanal R, Badal M. Stuck in the Heart: Embolized Strut Fracture of IVC Filter. Vasc Endovascular Surg. 2015 Apr-May;49(3-4):93-4. PMID: 26062976.
  39. Karmacharya P, Poudel DR, Pathak R, Rettew A, Alweis R. Acute hyperkalemia leading to flaccid paralysis: a review of hyperkalemic manifestations. J Community Hosp Intern Med Perspect. 2015 Jun 15;5(3):27993. PMID: 26091666;
  40. Pathak R, Khanal A, Poudel DR, Karmacharya P. Down with the Flu: Hyponatremia in a patient with influenza. N Am J Med Sci. 2015 May;7(5):227-8. PMID: 26110135
  41. Karmacharya P, Poudel DR, Pathak R, Donato AA, Ghimire S, Giri S, Aryal MR, Bingham CO 3rd. Rituximab-induced serum sickness: A systematic review. Semin Arthritis Rheum. 2015 Dec;45(3):334-40. PMID: 26199061.
  42. Pathak R, Karmacharya P, Giri S, Poudel DR, Aryal MR, Bhatt VR, Shamoun FE, Pandit A. Meta-analysis on efficacy and safety of new oral anticoagulants for venous thromboembolism prophylaxis in overweight and obese postarthroplasty patients. Blood Coagul Fibrinolysis. 2015 Sep;26(6):635-42. PMID: 26236940.
  43. Karmacharya P, Pathak R, Aryal MR, Giri S, Donato AA. Seasonal variation in acute gouty arthritis: data from Nationwide Inpatient Sample. Clin Rheumatol. 2015 Aug 9. PMID: 26255189.
  44. Pathak R, Poudel DR, Karmacharya P, Pathak A, Aryal MR, Mahmood M, Donato AA. YouTube as a Source of Information on Ebola Virus Disease. N Am J Med Sci. 2015 Jul;7(7):306-9. PMID: 26258077
  45. Pathak R, Giri S, Karmacharya P, Aryal MR, Poudel DR, Ghimire S, Jehangir A, Shaikh B, Rettew A, Donato AA. Meta-analysis on efficacy and safety of new oral anticoagulants for venous thromboembolism prophylaxis in elderly elective postarthroplasty patients. Blood Coagul Fibrinolysis. 2015 Dec;26(8):934-9. PMID: 26258674.
  46. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR, Martin MG. Seasonal variation of immune thrombocytopenic purpura related hospitalizations among adults in the USA: analysis of the nationwide inpatient sample database. Ther Adv Hematol. 2015 Aug;6(4):217-8. PMID: 26288716
  47. Aryal MR, Pandit A, Ghimire S, Pathak R, Karmacharya P, Poudel DR, Shamoun FE. Thromboprophylaxis with apixaban and the risk of pulmonary embolism in patients undergoing knee replacement surgery. J Community Hosp Intern Med Perspect. 2015 Sep 1;5(4):27889. PMID:26333856
  48. Fareedy SB, Rettew A, Karmacharya P, Jehangir A, Shaikh B, Pathak R. Erythema ab igne secondary to repeated heating pad use: an image case. J Community Hosp Intern Med Perspect. 2015 Sep 1;5(4):28335. PMID: 26333862
  49. Khanal R, Karmacharya P, Forman DA. Heparin-induced thrombocytopenia following coronary artery bypass grafting: a diagnostic dilemma. J Community Hosp Intern Med Perspect. 2015 Oct 19;5(5):28745. PMID: 26486110
  50. Khanal R, Karmacharya P, Pathak R, Poudel DR, Ghimire S, Alweis R. Do all patients with acquired methemoglobinemia need treatment? A lesson learnt. J Community Hosp Intern Med Perspect. 2015 Oct 19;5(5):29079. PMID: 26486118
  51. Pathak R, Khanal R, Aryal MR, Giri S, Karmacharya P, Pathak B, Acharya U, Bhatt VR. Sarcoidosis and Antiphospholipid Syndrome: A Systematic Review of Cases. N Am J Med Sci. 2015 Sep;7(9):379-83. PMID: 26605200
  52. Karmacharya P, Pathak R, Ghimire S, Shrestha P, Ghimire S, Poudel DR, Khanal R, Shah S, Aryal MR, Alweis RL. Upper Airway Hematoma Secondary to Warfarin Therapy: A Systematic Review of Reported Cases. N Am J Med Sci. 2015 Nov;7(11):494-502. PMID: 26713297
  53. Shrestha P, Adhikari J, Poudel D, Pathak R, Karmacharya P. Cortical Hemiballism: A Case of Hemiballismus Associated with Parietal Lobe Infarct. N Am J Med Sci. 2015 Dec;7(12):572-4. PMID: 26942135
  54. Pathak R; Karmacharya P, Alweis RL. Seasonal Variation of Rectal Foreign Bodies: Data from Nationwide Inpatient Sample. N Am J Med Sci. 2016 Apr;8(4):191-3. PMID: 27213144
  55. Karmacharya P, Donato AA, Aryal MR, Ghimire S, Pathak R, Shah K, Shrestha P, Poudel D, Wasser T, Subedi A, Giri S, Jalota L, Olivé A. RS3PE revisited: a systematic review and meta-analysis of 331 cases. Clin Exp Rheumatol. 2016 May-Jun;34(3):404-15. Epub 2016 Mar 25. Review. PMID: 27050250
  56. Poudel DR, Karmacharya P, Donato A. Risk of acute gout among active smokers: data from nationwide inpatient sample. Clin Rheumatol. September 2016:1-4. PMID: 27658418
  57. Shrestha P, Poudel D, Pathak R, Karmacharya P. Effect of statins on the mortality of bacteremic patients: A systematic review and meta-analysis of clinical trials. North Am J Med Sci. 2016;8(6):250. PMID: 27500129
  58. Tachamo N, Nazir S, Lohani S, Karmacharya P. Strongyloidiasis in the immunocompetent: an overlooked infection. J Community Hosp Intern Med Perspect. 2016 Sep 7;6(4):32038. eCollection 2016. PMID: 27609726
  59. Ukaigwe A, Shrestha P, Karmacharya P, Hussain SK, Samii S, Gonzalez MD, Wolbrette D, Naccarrelli GV. Meta-analysis of efficacy and safety of apixaban and uninterrupted apixaban therapy compared to vitamin K antagonists in patients undergoing catheter ablation for atrial fibrillation. J Interv Card Electrophysiol. 2017 Mar;48(2):223-233. Epub 2016 Oct 22. Review. PMID: 27771820.
  60. Pathak R, Bhatt VR, Karmacharya P, Aryal MR, Donato AA. Medical and Economic Burden of Heparin-Induced Thrombocytopenia: A Retrospective Nationwide Inpatient Sample (NIS) Study. J Hosp Med. 2017 Feb;12(2):94-97. PMID: 28182804.
  61. Poudel DR, Karmacharya P. Obesity and outcomes in rheumatoid arthritis. Semin Arthritis Rheum. 2017 Mar 21. pii: S0049-0172(16)30416-4. PMID: 28478965.
  62. Giri S, Pathak R, Aryal MR, Karmacharya P, Bhatt VR. Second primary malignancy in acute promyelocytic leukemia: a Surveillance, Epidemiology and End Results database study. Future Oncol. 2017 Jul;13(17):1455-1457. Epub 2017 Jul 7. PubMed PMID: 28685606.
  63. Dhital R, Poudel DR, Tachamo N, Gyawali B, Basnet S, Shrestha P, Karmacharya P. Ischemic Stroke and Impact of Thyroid Profile at Presentation: A Systematic Review and Meta-analysis of Observational Studies. J Stroke Cerebrovasc Dis. 2017 Aug 15. PMID:28821377.
  64. Poudel D, George M, Dhital R, Karmacharya P, Sandorfi N, Derk C. Mortality, Length of Stay and Cost of Hospitalization among Patients with Systemic Sclerosis: Results from the National Inpatient Sample. Rheumatology (Oxford). 2018 Sep 1;57(9):1611-1622. PMID: 29868788
  65. Shrestha P, Poudel DR, Dhital R, Karmacharya P. Seasonal and Regional Variation of Asthma-related Hospitalizations and Mortality among adults in the United States. Ann Allergy Asthma Immunol. 2018 Jul 4. PMID: 29981441
  66. Shrestha P, Le B, Wagner B, Pompella W, Karmacharya P. Immunoglobulin G4 Sclerosing Cholangitis: An Unusual Cause of Obstructive Jaundice-Case Report and Literature Review. Case Rep Rheumatol. 2018 Aug 23;2018:9602373. eCollection 2018. PMID: 30210896
  67. Shrestha P, Dhital R, Poudel D, Donato A, Karmacharya P, Craig T. Trends in hospitalizations related to anaphylaxis, angioedema and urticaria in the United States. Ann Allergy Asthma Immunol. 2019 Feb 12. PMID: 30769181
  68. Shrestha P, Karmacharya P, Wang Z, Donato A, Joshi AY. Impact of IVIG vs. SCIG on IgG trough level and infection incidence in primary immunodeficiency diseases: A systematic review and meta-analysis of clinical studies. World Allergy Organ J. 2019 Oct 9;12(10):100068. PMID: 31641401
  69. Dhital R, Pandey RK, Poudel DR, Oladunjoye O, Paudel P, Karmacharya P. All-cause hospitalizations and mortality in systemic lupus erythematosus in the US: results from a national inpatient database. Rheumatol Int. 2019 Nov 26. [Epub ahead of print] PMID: 31773392
  70. Karmacharya P, Duarte-Garcia A, Dubreuil M, Murad MH, Shahukhal R, Shrestha P, Myasoedova E, Crowson CS, Wright K, Davis JM 3rd. The Effect of Therapy on Radiographic Progression in Axial Spondyloarthritis: A Systematic Review and Meta-Analysis. Arthritis Rheumatol. 2020 Jan 20. Review. PMID: 31960614 (featured at SPARTAN 2020 annual meeting)
  71. Myasoedova E, Karmacharya P, Duarte-Garcia A, Davis JM 3rd, Murad MH, Crowson CS. Effect of statin use on the risk of rheumatoid arthritis: A systematic review and meta-analysis. Semin Arthritis Rheum. 2020 Apr 9:S0049-0172(20)30081-0. PMID: 32291099
  72. Karmacharya P, Shahukhal R, Ogdie A. Risk of Malignancy in Spondyloarthritis: A Systematic Review. Rheum Dis Clin North Am. 2020 Aug;46(3):463-511. Epub 2020 Jun 11. PMID: 32631600 Review
  73. Wilton KM, Achenbach SJ, Karmacharya P, Ernste FC, Matteson EL, Crowson CS. Erectile Dysfunction in Men with Psoriatic Arthritis: A Population-based Cohort Study. J Rheumatol. 2020 Oct 15:jrheum.200903. PMID: 33060322
  74. Duarte-García A, Myasoedova E, Karmacharya P, Hocaoğlu M, Murad MH, Warrington KJ, Crowson CS. Effect of omega-3 fatty acids on systemic lupus erythematosus disease activity: A systematic review and meta-analysis. Autoimmun Rev. 2020 Oct 22:102688. PMID: 33131703 Review.
  75. Karmacharya P, Shahukhal R, Crowson CS, Murad MH, Davis JM 3rd, Shrestha P, Bekele D, Wright K, Chakradhar R, Dubreuil M. Effects of Therapies on Cardiovascular Events in Ankylosing Spondylitis: A Systematic Review and Meta-Analysis. Rheumatol Ther. 2020 Dec;7(4):993-1009. Epub 2020 Nov 10. PMID: 33170493
  76. Karmacharya P, Wright K, Achenbach SJ, Bekele D, Crowson CS, Ogdie A, Duarte-García A, Ernste FC, Tollefson MM, Davis JM 3rd. Diagnostic Delay in Psoriatic Arthritis: A Population Based Study. J Rheumatol. 2021 Feb 15:jrheum.201199. PMID: 33589556 (JRheum Editor’s pick, Sep 2021)
  77. Karmacharya P, Ogdie A, Eder L. Psoriatic arthritis and the association with cardiometabolic disease: a narrative review. Ther Adv Musculoskelet Dis. 2021 Mar 2;13:1759720X21998279. eCollection 2021.PMID: 33737966
  78. Karmacharya P, Crowson CS, Bekele D, Achenbach SJ, Davis JM 3rd, Ogdie A, Duarte-García A, Ernste FC, Maradit-Kremers H, Tollefson MM, Wright K. The Epidemiology of Psoriatic Arthritis over 5 Decades: A Population-Based Study. Arthritis Rheumatol. 2021 Mar 28. PMID: 33779070 (A&R Editor’s Pick, Oct 2021)
  79. Karmacharya P, Chakradhar R, Ogdie A. The epidemiology of psoriatic arthritis: A literature review. Best Pract Res Clin Rheumatol. 2021 May 18:101692, PMID: 34016528
  80. Dhital R, Oke I, Donato A, Paudel A, Poudel DR, Paudel P, Karmacharya P. Trends in hospitalizations for vertebral compression fracture in ankylosing spondylitis: data from the National Inpatient Sample 2000-2014. Clin Rheumatol. 2021 Jul 5. PMID: 34224028
  81. Chaudhary H, Bohra N, Syed K, Donato A, Murad MH, Karmacharya P. All-Cause and Cause-Specific Mortality in Psoriatic Arthritis and Ankylosing Spondylitis: A Systematic Review and Meta-Analysis. Arthritis Care Res (Hoboken). 2023 May;75(5):1052-1065. PMID: 34788902
  82. Karmacharya P, Wright K, Achenbach SJ, Crowson CS, Ogdie A, Bekele D, Duarte-García A, Ernste FC, Tollefson MM, Davis Iii JM. Time to transition from psoriasis to psoriatic arthritis: A population-based study. Semin Arthritis Rheum. 2022 Feb;52:151949. PMID: 35000786
  83. Karmacharya P, Stull C, Stephens-Shields A, Husni ME, Scher JU, Craig E, Fitzsimmons R, Reddy SM, Magrey MN, Ogdie A, Walsh JA. Responsiveness and Minimum Clinically Important Difference in Patient-Reported Outcome Measures Among Patients With Psoriatic Arthritis: A Prospective Cohort Study. Arthritis Care Res (Hoboken). 2023 Oct;75(10):2182-2189. PMID: 36913210
  84. Karmacharya P, Gupta S, Shahukhal R, Khanal R, Murad MH, Gensler LS. Effect of Biologics in Subgroups of Axial Spondyloarthritis Based on Magnetic Resonance Imaging and C-Reactive Protein: A Systematic Review and Meta-Analysis. ACR Open Rheumatol. 2023 Sep;5(9):481-489. Epub 2023 Aug 7. PMID: 37551049
  85. Karmacharya P, Crowson CS, Lennon RJ, Poudel D, Davis JM 3rd, Ogdie A, Liew JW, Ward MM, Ishimori M, Weisman MH, Brown MA, Rahbar MH, Hwang MC, Reveille JD, Gensler LS. Multimorbidity phenotypes in ankylosing spondylitis and their association with disease activity and functional impairment: Data from the prospective study of outcomes in ankylosing spondylitis cohort. Semin Arthritis Rheum. 2023 Nov 7;64:152282. PMID: 37995469
  86. Karmacharya P, Chakradhar R, Hulshizer CA, Gunderson TM, Ogdie A, Davis Iii JM, Wright K, Tollefson MM, Duarte-García A, Bekele D, Maradit-Kremers H, Crowson CS. Multimorbidity in psoriasis as a risk factor for psoriatic arthritis: a population-based study. Rheumatology (Oxford). 2025 Apr 1;64(4):2199-2203. doi: 10.1093/rheumatology/keae040. PMID: 38291896; PMCID: PMC11962958.
  87. Karmacharya P, Crofford LJ, Byrne DW, Stephens-Shields A, Husni ME, Scher JU, Craig E, Fitzsimmons R, Reddy SM, Magrey MN, Walsh JA, Ogdie A. Psoriatic arthritis phenotype clusters and their association with treatment response: a real-world longitudinal cohort study from the psoriatic arthritis research consortium. Ann Rheum Dis. 2025 Feb;84(2):253-261. doi: 10.1136/ard-2024-226150. Epub 2025 Jan 2. PMID: 39919898; PMCID: PMC11822222.

Books, Book Chapters, Invited Review Articles:

  1. Elite Test Preparation: Board review course book– Rheumatology section April 2015, last revised April 2018

Letters to Editor: (peer-reviewed journals)

  1. Karmacharya P, Pathak R, Aryal MR, Donato AA. Fibrinolysis in intermediate risk pulmonary embolism: too much risk for too little reward? Int J Cardiol. 2014 Oct 20;176(3):1290-1. PMID: 25115261.
  2. Karmacharya P, Poudel DR, Pathak R, Rettew A, Alweis R. Response to Letter. J Community Hosp Intern Med Perspect. 2015 Sep 1;5(4):29308. PMID: 26333867
  3. Karmacharya P, Balls-Berry JE, Davis JM 3rd. True Difference or Detection Bias: Racial Differences in Clinical Features and Comorbidities in Ankylosing Spondylitis in Ankylosing Spondylitis in the United States. J Rheumatol. 2020 Feb 15. pii: jrheum.191399. PMID: 32062596
  4. Karmacharya P, Duarte-Garcia A, Dubreuil M, Murad MH, Shahukhal R, Shrestha P, Myasoedova E, Crowson CS, Wright K, Davis JM 3rd. Reply: Response to Letter to the Editor. Arthritis Rheumatol. 2020 Jul 20. PMID: 32686914